The global mobilization to combat and ultimately end the epidemics of HIV, tuberculosis (TB), and malaria has transformed the global health field, in large measure through the creation of innovative, results-focused programs for funding and delivering health services. These include the Global Fund to Fight AIDS, Tuberculosis and Malaria (founded in 2002); the President’s Emergency Plan for AIDS Relief (PEPFAR, founded in 2003); the President’s Malaria Initiative (PMI, founded in 2005); and bilateral TB funding through the U.S. Agency for International Development (USAID). PEPFAR alone accounted for nearly two thirds of all international HIV assistance in 2017, while the Global Fund contributed almost 60% of international funding for malaria control. In addition to its bilateral programs for these three diseases, the U.S. is the leading donor to the Global Fund.
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