2008 Research Fellowships, Grants, and Awards
All projects listed below were supported by amfAR during the period October 1, 2007, to September 30, 2008. Grants funded during fiscal year 2008 but awarded in previous years are shown with the year of the award in parentheses.
Mathilde Krim Fellowships in Basic Biomedical Research
Research Fellowships
Research Grants
Research Awards
Mathilde Krim Fellowships in Basic Biomedical Research
Preventing HIV Transmission
Identification and biological characteristics of transmitted HIV-1
Brandon Keele, Ph.D.
University of Alabama at Birmingham
Birmingham, AL
$119,868
Generation of stable HIV-1 Env trimers through virus evolution
Rogier Sanders, Ph.D.
Academic Medical Center, University of Amsterdam
Amsterdam, Netherlands
$125,000
Optimizing HIV Treatment
Modulation of HIV reverse transcription and nuclear integration by TRIM5
Felipe Diaz-Griffero, Ph.D.
Dana Farber Cancer Institute
Boston, MA
$125,000
HIV Tat-mediated transfer of P-TEFb to nascent RNA and its inhibition
Ivan D’Orso, Ph.D.
University of California at San Francisco
San Francisco, CA
$125,000
Biophysical and structural studies of the HIV integrase DNA complex
Kushol Gupta, Ph.D.
The University of Pennsylvania School of Medicine
Philadelphia, PA
$125,000
Morphogenesis and storage of HIV-1 particles
Nolwenn Jouvenet, Ph.D.
Aaron Diamond AIDS Research Center
New York, NY
$125,000
Ultrapotent inhibitors of wild-type and multi-drug resistant HIV
Bruno Marchand, Ph.D.
University of Missouri-Columbia
Columbia, MO
$125,000
Maintenance of drug resistance mutations and HIV-1 evolutionary adaptation
Morgane Rolland, Ph.D.
University of Washington
Seattle, WA
$125,000
Pursuing HIV Eradication
Novel post-transcriptional mechanisms of HIV-1 latency and reactivation
Kara Lassen, Ph.D.
Case Western Reserve University
Cleveland, OH
$125,000
Novel post-transcriptional mechanisms of HIV-1 latency and reactivation
Kara Lassen, Ph.D.
The J. David Gladstone Institutes
San Francisco, CA
$102,340 (transfer)
Research Fellowships
Preventing HIV Transmission
The role of mental health issues in HIV acquisition among female drug users
Gail Gilchrist, Ph.D.
L’Institut Municipal d’Investigacio Medica
Barcelona, Catalonia, Spain
$124,915
Anal intercourse, STIs, and HIV among STD clinic clients
Marjan Javanbakht, Ph.D.
University of California, Los Angeles
Los Angeles, CA
$112,193 (2007)
Colorectal responses to HIV-1 and modulation by microbicides
Carolina Herrera, Ph.D.
St George’s University of London
London, UK
$125,000 (2007)
HIV mucosal transmission in humanized mice model
Liguo Zhang, Ph.D.
University of North Carolina at Chapel Hill
Chapel Hill, NC
$99,000 (2006)
Optimizing HIV Treatment
What they’re not telling me: Veterans, trust, and HIV management
Kristin Mattocks, Ph.D.
Yale University
New Haven, CT
$108,480
Impulsivity, drug abuse, and HIV medication adherence: An fMRI study
Christina Meade, Ph.D.
Harvard Medical School—McLean Hospital/Massachusetts General Hospital
Belmont, MA
$124,000 (2007)
Viral persistance in the MGT of RT-SHIV infected macaques on HAART
Miranda Xhilaga, Ph.D.
Monash University
Melbourne, Australia
$125,000 (2007)
Molecular mechanisms of the HIV-1 coreceptor CCR5 function
Gabriel Birrane, Ph.D.
Beth Israel Deaconess Medical Center
Boston, MA
$99,000 (2006)
Designing inducible Pol II systems for RNA interference of HIV-1
Hoshang Unwalla, Ph.D.
Beckman Research Institute of the City of Hope
Duarte, CA
$99,000 (2006)
The APOBEC3G-Vif interaction as a new HIV therapeutic target
Hendrik Huthoff, Ph.D.
King’s College London
London, UK
$99,000 (2005)
Mechanistic study of retroviral entry and restriction in vitro
Virginie Sandrin, Ph.D.
University of Utah
Salt Lake City, UT
$99,000 (2005)
Mechanism of postentry restriction of HIV-1 by TRIM5alpha
Chisu Song, Ph.D.
Vanderbilt University School of Medicine
Nashville, TN
$99,000 (2005)
Pursuing HIV Eradication
In vivo modeling of HIV persistence and its eradication
Paul Denton, Ph.D.
University of Texas Southwestern Medical Center at Dallas
Dallas, TX
$125,000
Quantitative fMRI of CNS-T ART on HIV brain reservoirs
Beau Ances, M.D., Ph.D.
University of California San Diego
San Diego, CA
$125,000 (2006)
HIV-1 cell-cell spread in viral dissemination and persistence
Fedde Groot, M.Sc.
The Sir William Dunn School of Pathology, University of Oxford
Oxford, UK
$124,882 (2006)
Virologic correlates of subtype-A HIV transmission
Richard Haaland, Ph.D.
Emory University
Atlanta, GA
$99,000 (2006)
Role of Tat methylation in HIV latency
Sara Pagans, Ph.D.
The J. David Gladstone Institutes
San Francisco, CA
$125,000 (2006)
Macrophage matrix metalloproteinases role in persistence of HIV-1 in CNS
Nicole Webster, Ph.D.
Macfarlane Burnet Institute for Medical Research and Public Health, Ltd.
Melbourne, Victoria, Australia
$125,000 (2006)
HIV reservoir in central memory T cells
Nicolas Chomont, Ph.D.
Université de Montréal, Centre de Recherches du CHUM
Montréal, Québec, Canada
$83,100 (2005)
Identification of novel host factors for HIV replication
Lei Fang, M.D., Ph.D.
Salk Institute for Biological Studies
La Jolla, CA
$99,000 (2005)
Kinetics of HIV reactivation in latently infected T cells
Young Kyeung Kim, Ph.D.
Case Western Reserve University
Cleveland, OH
$99,000 (2005)
Human cellular factors that restrict HIV infection
Susana Valente, Ph.D.
Columbia University in the City of New York
New York, NY
$99,000 (2005)
Research Grants
Preventing HIV Transmission
Neurocognitive factors in the relationship between drug use and risky sex
Sarit Golub, Ph.D.
Research Foundation of the City of New York
Flushing, NY
$120,000
HIV prevention efficacy beliefs about male circumcision in South Africa
Joanne Mantell, Ph.D.
HIV Center for Clinical and Behavioral Studies at the New York State Psychiatric Institute and Columbia University
New York, NY
$119,906
Minority stress, social support, and sexual risk in South African MSM
Theodorus Sandfort, Ph.D.
Research Foundation for Mental Hygiene, Inc.
New York, NY
$119,836
HIV conspiracy beliefs among MSM in inner-city slum area of Johannesburg
Waimar Tun, Ph.D.
The Population Council
New York, NY
$119,997
Development of a standard rectal microbicide delivery device
Alex Carballo-Diéguez, Ph.D.
Research Foundation for Mental Hygiene, Inc.
New York, NY
$119,992 (2007)
Colorectal explants to study HIV transmission and microbicides
Charlene Dezzutti, Ph.D.
Magee-Womens Research Institute and Foundation
Pittsburgh, PA
$120,000 (2007)
Epithelial injury and HIV penetration after simulated ejaculation
Craig Hendrix, M.D.
Johns Hopkins University School of Medicine
Baltimore, MD
$120,000 (2007)
How to test: Policy and practice after the CDC recommendations
Lori Leonard, Sc.D.
Johns Hopkins School of Public Health
Baltimore, MD
$120,000 (2007)
Mediation effect of network function on HIV risk behavior among Chinese
Hongie Liu, Ph.D.
School of Medicine, Virginia Commonwealth University
Richmond, VA
$119,988 (2007)
Anal sex practices in high-risk South African women and men
Joanne Mantell, Ph.D.
Research Foundation for Mental Hygiene, Inc.
New York, NY
$119,946 (2007)
Rectal transmission of HIV-1 in a novel mouse model
Roberto Speck, M.D.
Division of Infectious Diseases, Department of Internal Medicine, University Hospital of Zurich
Zurich, Switzerland
$119,822 (2007)
HIV-1 infection of mucosal lymphocytes and tissue explants
Benjamin K. Chen, M.D., Ph.D.
Mount Sinai School of Medicine
New York, NY (2006)
$90,000
Interaction of HIV with the macaque female genital tract
Thomas J. Hope, Ph.D.
Northwestern University
Chicago, IL
$90,000 (2006)
Understanding the properties of transmitted HIV-1 variants
Manish Sagar, M.D.
Brigham and Women’s Hospital/Harvard Medical School
Boston, MA
$90,000 (2006)
Optimizing HIV Treatment
Mistrust of evidence-based medicine affects health outcomes of Latinos
Scott Rhodes, Ph.D.
Wake Forest University Health Sciences
Winston-Salem, NC
$120,000
Recent changes in HIV testing recommendations: Impact on youth at risk
Marya Gwadz, Ph.D.
National Development and Research Institutes USA, Inc.
New York, NY (2007)
$119,598
Impact of PD-1 on the establishment and maintenance of the HIV-1 reservoir
Elias Haddad, Ph.D.
Université de Montréal, Centre de Recherche du CHUM
Montréal, Québec, Canada
$107,568 (2007)
Establishment of the HIV reservoir during acute infection
Stephen Kent, M.D.
University of Melbourne
Melbourne, Victoria, Australia
$120,000 (2007)
CDC HIV testing guidelines: Unresolved ethical concerns
Roland Merchant, M.D., Sc.D.
Rhode Island Hospital
Providence, RI
$120,000 (2007)
AHI awareness and entry into care among high risk populations
Robert Remien, Ph.D.
Research Foundation for Mental Hygiene, Inc.
New York, NY
$119,654 (2007)
The impact of stigma on access to HIV treatment and care
Jennifer Sayles, M.D.
University of California, Los Angeles, David Geffen School of Medicine
Los Angeles, CA
$120,000 (2007)
Immunologic benefits of CCR5 inhibitor intensification
Robert Shafer, M.D.
Palo Alto Veterans Administration Medical Center and Stanford University
Palo Alto, CA
$107,644 (2007)
Pursuing HIV Eradication
In vivo virus persistence during suppressive therapy in the RT-SHIV model
Zandrea Ambrose, Ph.D.
University of Pittsburgh
Pittsburgh, PA
$120,000
Animal model for controlled SIV infection
Cristian Apetrei, M.D., Ph.D.
Tulane University
New Orleans, LA
$119,687
Autophagy and intracellular HIV in macrophages
Vojo Deretic, Ph.D.
University of New Mexico Health Sciences Center
Albuquerque, NM
$120,000
HDAC inhibition and chromatin remodeling to disrupt proviral latency
David Margolis, M.D.
University of North Carolina at Chapel Hill
Chapel Hill, NC
$120,000
Treatment intensification: Effects on persistent viremia
Sarah Palmer, Ph.D.
Swedish Institute for Infectious Disease Control, Karolinska Institute
Solna, Sweden
$120,000
IL-7 and antigen driven proliferation generate distinct HIV reservoirs
Rafick-Pierre Sékaly, Ph.D.
Université de Montréal, Centre de Recherche du CHUM
Montréal, Québec, Canada
$106,164
Quantification of HIV provirus: Integration and replication competence
Celsa Spina, Ph.D.
Veterans Medical Research Foundation
San Diego, CA
$117,600
Genetic screens for inhibitors of HIV latency
Paul Bieniasz, Ph.D.
Aaron Diamond AIDS Research Center
New York, NY
$120,000 (2006)
HIV controllers: A potential model for HIV eradication
Steven Deeks, M.D.
University of California, San Francisco
San Francisco, CA
$120,000 (2006)
The role of CCR7 ligands and dendritic cells in latent HIV infection
Sharon Lewin, F.R.A.C.P., Ph.D.
Monash University
Melbourne, Victoria, Australia
$120,000 (2006)
Reservoirs of SIV in long term nonprogressors in rhesus macaques
Binhua Ling, M.D., Ph.D.
Tulane National Primate Research Center
Covington, LA
$120,000 (2006)
The GI tract may be a reservoir of ongoing viral replication during HAART
Martin Markowitz, M.D.
Aaron Diamond AIDS Research Center
New York, NY
$120,000 (2006)
Role of lymph node dendritic cells in HIV infection
David McDonald, Ph.D.
Case Western Reserve University
Cleveland, OH
$120,000 (2006)
Identifying the major tissue reservoirs in SIV/SHIV infected macaques
Bapi Pahar, Ph.D.
Tulane National Primate Research Center
Covington, LA
$120,000 (2006)
Effects of valproic acid therapy on gut mucosal HIV reservoirs
Jean-Pierre Routy, M.D.
McGill University Health Centre
Montréal, Québec, Canada
$119,827
Research Awards
Preventing HIV Transmission
Modeling the impact of a rectal microbicide
London School of Hygiene and Tropical Medicine
London, UK
$120,000
Rectal microbicides: Investment and advocacy
AIDS Foundation of Chicago
Chicago, IL
$1,000
Pursuing HIV Eradication
Viral persistence and eradication workshop
Treatment Action Group
New York, NY
$20,000